Estrofem 2 Mg 28 Tablets

1. What ESTROFEM is and what it is used for

Estrofem is a Hormone Replacement Therapy (HRT). Contains the female sex hormone estradiol. Estrofem is used after menopause, especially in women who have had their womb removed (had a hysterectomy) and therefore do not need combined estrogen/progestagen therapy.

Estrofem is used to reduce postmenopausal symptoms.

During menopause, the amount of estrogen produced in the female body decreases. This condition can cause symptoms such as face, neck, and chest warmth (hot flashes). Estrofem reduces such postmenopausal symptoms. Estrofem should only be prescribed if your symptoms (such as post-menopausal hot flashes) seriously interfere with your daily life.

Experience in the treatment of women over 65 years of age is limited.

2.How to use ESTROFEM?

Always use Estrofem exactly as your doctor has told you. If you are unsure, ask your doctor or pharmacist.

If you have had your uterus removed or are not experiencing vaginal bleeding and you are not using other hormone therapy products, you can start treatment on any suitable day.

Take one tablet every day at the same time of day. After you finish all 28 tablets in the calendar and cycle box, continue the treatment with a new calendar and cycle box without a break.

Your doctor will prescribe the lowest dose that will treat your symptoms as soon as possible. If you think this dose is too strong or too weak, talk to your doctor.

If you have had your uterus removed and you have not had a condition called endometriosis (the presence of tissue outside the uterus), your doctor will not additionally prescribe a progestagen (other female hormone).

If you have ever used other HRT products, please ask your doctor or pharmacist when you should start using Estrofem.

If you have breakthrough bleeding or spotting, especially within the first few months of taking HRT, there is usually no need to worry (See section 2 HRT and cancer, Excessive thickening of the intrauterine tissue (endometrial hyperplasia) and cancer of the intrauterine tissue (endometrial cancer) for more information).
Application route and method

Take Estrofem by mouth.

Take the tablets with a sufficient amount of liquid (eg a glass of water).

For the use of the calendared and recirculating box, see the "Usage of Estrofem 2 mg film-coated tablet" section at the end of this Instructions for Use.
different age groups
Use in the elderly

Experience in the treatment of women over 65 years of age is limited.
Special use cases
Kidney failure:

Estrogens can cause fluid retention and therefore patients with cardiac or renal impairment should be carefully observed. Since the circulating levels of the active ingredients of Estrofem are expected to increase, patients with end-stage renal disease should be followed closely.
Liver failure:

It should never be used in case of acute liver disease or a history of liver disease that prevents liver function tests from returning to normal.

In case of liver disorders (eg liver adenoma), treatment should be closely monitored, and if jaundice or hepatic dysfunction occurs, treatment should be discontinued.

If you have an impression that the effect of Estrofem is too strong or weak, talk to your doctor or pharmacist.
If you use more ESTROFEM than you should

An overdose of Estrofem may make you feel sick or vomit.

If you have used more than you should use from Estrofem, talk to a doctor or pharmacist.
If you forget to use ESTROFEM

Do not take a double dose to make up for forgotten doses.

If you forget to take your tablet at the usual time, take it within 12 hours. If more than 12 hours have passed, discard the forgotten tablet and continue the treatment as usual the next day. If you have a still uterus, forgetting a dose may increase the chance of breakthrough bleeding and spotting.

3. What are the possible side effects?

Like all medicines, there may be side effects in people who are sensitive to the substances contained in ESTROFEM.

If any of the following occur, stop using ESTROFEM and IMMEDIATELY inform your doctor or go to the nearest hospital emergency department.

Hypersensitivity (hypersensitivity)/allergy (Uncommon side effects - affects 1 to 10 people in 1000)

Although an uncommon case, hypersensitivity/allergy may occur. Hypersensitivity/allergy may include one or more of the following symptoms: urticaria (hives), itching, swelling, difficulty in breathing, low blood pressure (coldness and dullness of the skin, rapid heartbeat), dizziness, sweating, these are anaphylactic reaction/shock may have symptoms. If any of the above-mentioned symptoms occur, stop taking Estrofem and seek emergency medical help.

These are all very serious side effects.

If you have one of these, you may need emergency medical attention or hospitalization.

The frequency of possible side effects is listed below in the following order:

Very common (affects more than 1 person in 10)

Common (affects 1 to 10 people in 100)

Uncommon (affects 1 to 10 people in 1000)

Rare (affects 1 to 10 people in 10,000)

Very rare (affects less than 1 in 10,000 people)

Not known (cannot be estimated from the available data).
Widespread
Depression
Headache
Abdominal pain
feeling sick (nausea)
leg cramps
Breast pain, breast tenderness, or breast enlargement
Edema (fluid retention)
Weight gain.
Unusual
Defect of vision
Formation of blood clots in the veins (venous embolism)
heartburn (dyspepsia)
Vomiting
bloating or gas
gallstones
Itching or urticaria (hives).